Marty Makary

by James A. Bacon

For insight into Governor Glenn Youngkin’s approach to managing the COVID-19 epidemic, read the latest column by Marty Makary, a research professor at the Johns Hopkins University, in The Wall Street Journal. He argues that society is paying a high cost for disparaging the immunological resistance that arises from exposure to the COVID virus. 

Some excerpts from his column:

Last week the [Centers for Disease Control] released data from New York and California, which demonstrated natural immunity was 2.8 times as effective in preventing hospitalization and 3.3 to 4.7 times as effective in preventing Covid infection compared with vaccination.

Yet the CDC spun the report to fit its narrative, bannering the conclusion “vaccination remains the safest strategy.” It based this conclusion on the finding that hybrid immunity — the combination of prior infection and vaccination — was associated with a slightly lower risk of testing positive for Covid. But those with hybrid immunity had a similar low rate of hospitalization (3 per 10,000) to those with natural immunity alone. In other words, vaccinating people who already had Covid didn’t significantly reduce the risk of hospitalization.

(The CDC study can be found here.)

Some have argued that the duration of natural immunity is unknown. But until Makary and his JHU colleagues did so, no one had actually conducted a study to find out how long it lasted. “We found that among 295 unvaccinated people who previously had Covid, antibodies were present in 99% of them up to nearly two years after infection. We also found that natural immunity developed from prior variants reduced the risk of infection with the Omicron variant.” By contrast, the effectiveness of the Moderna vaccine declines after six months.

“The CDC study and ours confirm what more than 100 other studies on natural immunity have found: The immune system works,” Makary writes. Public health officials, he says, have a lot of explaining to do.

They used the wrong starting hypothesis, ignored contrary preliminary data, and dug in as more evidence emerged that called their position into question.

And they owe an apology to Americans who lost their jobs to vaccination mandates on the false premise that only vaccination could prevent virus spread and hospitalizations.

If you are an adult who has never contracted COVID-19, it usually does make sense to get vaccinated. But that argument breaks down for people who have survived COVID and acquired natural immunities. Public policy nationally and here in Virginia has never made the distinction between unvaxxed Americans with naturally-acquired immunities and those without. Mandates applied to everyone indiscriminately.

I have written about the distinction between COVID survivors and the unexposed in relation to university mandates that all students and employees get vaccinated, regardless of previous exposure. At the University of Virginia those who refused to get vaccinated were expelled. I can’t speak for other universities, which I have not followed as closely, but UVa tested for COVID extensively and knew who had been exposed and who had not. But the administration never made that distinction in its policy analysis. It never allowed exemptions for students who could document their exposure. Students had the choice of submitting or leaving.

At George Mason University, professor Todd Zywicki managed to win a medical exemption from the university’s mandatory vaccination policy — but he had to file a lawsuit first. And even then, he had to agree to undergo weekly testing, which vaccinated individuals did not. The lawsuit presented a substantial body of scientific evidence suggesting that COVID survivors benefited from natural immunity, but the arguments he presented were ignored by both the Northam administration and other public universities.

The issue may be academic now. Thanks to the vax mandates, the overwhelming majority of students, faculty and staff at Virginia’s public universities have been vaccinated. At UVa the administration saw to that when, in anticipation of Youngkin’s assuming office on Jan. 15, it accelerated its vaccination deadlines to Jan. 14.

However the epidemic plays out, there is little doubt that Youngkin will handle things differently than Northam did. The mandated-vaccination issue is still alive for private employers, including hospitals. Advocates of mandates, restrictions and other tools of social control may emphasize different data from the CDC acquired-immunity study than Makary did, but Youngkin is listening to Makary.


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13 responses to “Makary on Mandates”

  1. Virginia Gentleman Avatar
    Virginia Gentleman

    Makary (a surgeon) is at it again. After his last WSJ op-ed on the US reaching heard immunity by last April was completely wrong – he grabs the bat and takes another swing.

    1. Do you happen to have the quote about the U.S. reaching herd immunity? I’d like to read the quote in context.

      1. Yup, he got that prediction wrong, no question. COVID is a lot more dynamic a disease than he gave it credit for being then. Someone should ask him what, if anything, he learned from that error.

        1. Thank God those great medical professionals at the CDC and NIH have been 100% correct from the beginning…….

  2. Dick Hall-Sizemore Avatar
    Dick Hall-Sizemore

    I am not surprised that having COVID results in “natural immunity”. In fact, I would have been surprised if it did not.

    I would not have any problem exempting folks with natural immunity from mandated vaccinations. The problem is, and has been, how to document that natural immunity. It would not be enough to go with someone’s word that they had had COVID. From what little I have read, there is still debate over the accuracy of antibody tests. Furthermore, they can be expensive.

    https://jamanetwork.com/journals/jama/fullarticle/2785530

    But, I would rather acquire immunity via a vaccination than through contracting the disease. With vaccination, the risk of serious illness and death is much lower and there is the issue of long-COVID. I have not seen any reports of long-COVID being associated with vaccination.

    By the way, despite Makary’s views, Johns Hopkins is still recommending vaccination for those with natural immunity.

    https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/covid-natural-immunity-what-you-need-to-know

    Finally, I would hope Youngkin would handle things differently than Northam did. After all, Youngkin has the benefit of the scientific having two years of experience to learn about the disease, develop vaccines, and develop treatments.

    1. Stephen Haner Avatar
      Stephen Haner

      The study cited was 100% pre Omicron. I suspect that variant blows it all to hell anyway. That’s what I had, and I’m happy now to have the benefits of both the full Pfizer suite and I hope now some added natural immunity.

      I too remember (and cited at the time) Makary’s early declaration of herd immunity. Boy was that wrong. Next expert! I have heard nothing out of the new governor that questions the utility of vaccination, and I hope that doesn’t come. I’m sorry Jim keeps nosing around the issue, bringing it up constantly and undermining the efforts to persuade the hold outs. (Not that any reader here is wavering in their opinions, either way.)

      Very, very foolish to skip the shots unless you have a known medical problem they would exacerbate.

      1. killerhertz Avatar
        killerhertz

        Agreed the war on natural immunity has undermined public health and will continue to do so.

        I had COVID twice. The first time was early in the pandemic (1st week of March 2020) for business travel coming back from LA. I wore a vented N95 on the plane (so much that did). Despite going to the ER to get tested, they refused. 2 days of flu like symptoms (fever, aches, GI). I paid for a serology test to confirm my infection 4 months later in June. Aside from being very cautious for the 1st month, our family never really modulated our social behavior, including 2 vacations that summer. Never had an issue and sickness was very minimal in 2020. More recently our kids brought COVID home from school (presumably Omicron). A lot of the kids are/were out now with infection and/or close contact. I was unvaxed however both my fully vaxed (pfizer and J&J both in June 2021) wife and mother in law tested positive and became sick with flu like symptoms. I was probably the least ill of everyone with 1 day of mild flu like symptoms (slight fever and body aches).

      2. Packer Fan Avatar
        Packer Fan

        And yet there’s Fauci and all of his incorrect proclamations……………

        1. Stephen Haner Avatar
          Stephen Haner

          Have you read the Scott Atlas book? Ay caramba…devastating if true…although he claims Birx was mainly driving that train.

          Jim, in answer to your earlier question, the problem with the first Makary “nearing herd immunity” claim was the timing, which I think was actually in 2020 in a WSJ column. So before Winter ’21, September ’21 and the December ’21 waves.

          I know the usual suspects go ballistic over this comparison, but it is just the same problem as with the climate catastrophe models. Models ain’t the real world. Nature is too complicated.

          1. I did read the Atlas book, and I likewise found it to be a devastating indictment of Birx and Fauci, but most of all the media.

            I’ve also read Scott Gottlieb’s book, and I’m finishing up Michael Lewis’ book, “Premonition.”

            It’s been a clusterfark from beginning to end.

          2. Stephen Haner Avatar
            Stephen Haner

            Gottlieb was on CNBC again this morning with his consistent message that sure, having the disease protects you, but might not be for that long or for the next version and the smart move is to to supplement with the vaccine.

  3. Nancy Naive Avatar
    Nancy Naive

    It took 2 years to infect 70 million Americans with a loss of 800,000, and less than 6 months to vaccinate 100 million with a loss of, oh yeah, none.

    Cheaper, Faster, Better… it’s not the American Way.

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